I have been to Rome a couple of times. It is such a lovely place. I went to Christmas Mass at St Peter's Basilica when Pope John Paul II was pope. I have also been with my husband. Here are the things that I suggest you do if you visit here.
Mr B and I were staying Naples when we went to Rome. It was a 2 hour train ride, very impressed with the trains in Italy! It was less than a trip from Cambridge to London and more comfortable.
We walked most of Rome because like London any time spent underground you miss something! Also when we went the Metro only went west to east and north to South so it wasn't as convenient as you would have like. Here is the walking path we took.
Coloseum
You must take a trip to the Colosseum. Even though it is not the biggest one ever made, it is still impressive. This is where the gladiators fought to the death! Save yourself the time waiting in line and get a ticket from the Roman Forum or the Palatine.
Font Du Trevi
Make sure you pack a penny to throw into this fountain. The Fount du Trevi was made famous in the movice, La Dolce Vita. There is a old wives tale that if you throw a coin in the fountain, right hand over left shoulder with back to fountain, you will return to Rome. The good thing is that the money goes to help the poor.
The Vatican Museums
This is such a busy sight, you must book ahead to go to save yourself waiting hours in line. Failing that you can pay extra to one of the many tour guides outside. I am not exaggerating about these lines.
The Sistine Chapel is beautiful but a holy place so you need to cover your shoulders and be quiet.
Worth the visit!
St Peter's Bascillica
This is free to go into, there is a line but that is just to go through security.
You can also attend masses with the Pope but you have to get tickets. They are free. Please see this website for more information.
Roman Forum
The formun was the heart of Ancient Rome. Walk around the ruins and explore the past. The combined ticket you get here allows you to get int othe Colosseum and the Palatine.
Castel Angelo
This is the fortress for past popes and is connected to the Vatican via a tunnel underground. It is closed on Mondays.
Pantheon
This is free to get into and if it did not share the city with the Sistine Chapel, it would be visited more. This building dates back to AD 120. There is a hole in the dome and on the floor there is a drain to take away the water when it rains.
Capitoline Hill
This is Capital Hill and where the government has been since Ancient Rome.
Mouth of Truth
There is a legend that is you put your hand in the mouth and are a liar, it will bite your hand off. It is believed to be a manhole cover.